Polymeric SPE Cartridges

Clinisphere® PLS

  • Clinisphere PLS is a highly cross-linked polystyrene-divinylbenzene (PS-DVB) copolymer with high surface area (800 m2/g) and high capacity.
  • It is an excellent choice for extraction of polar analytes in aqueous solvents where traditional C18 and C8 sorbents are not advisable because they are not “wettable”.
  • It is ideal in screening applications where a broad range of analytes can be extracted.

Clinisphere® PXC

  • Clinisphere PXC is a highly cross-linked PS-DVB copolymer with sulfonic acid as the functional group.
  • It has both non-polar and cation exchange interactions and is therefore an excellent choice for extraction of basic organic compounds

Clinisphere® PXA

  • Clinisphere PXA is a highly cross-linked PS-DVB copolymer with a quaternary amino as the functional group.
  • It has both non-polar and anion exchange interactions and is therefore an excellent choice for extraction of acidic organic compounds, especially those containing carboxyl and phenolic hydroxyl.

Clinisphere® PWC

  • Planisphere PWC is a highly cross-linked PS-DVB copolymer with carboxyl as the functional group.
  • It has both non-polar and weak cation exchange interactions and is therefore an excellent choice for extraction of strong basic compounds.

Clinisphere® PWA

  • Clinisphere PWA is a highly cross-linked PS-DVB copolymer with piperazine as the functional group.
  • It has both non-polar and weak anion exchange interactions and is therefore an excellent choice for extraction of strong acidic compounds.
Clinisphere PLS Clinisphere PXC Clinisphere PXA Clinisphere PWC Clinisphere PWA
Base material Porous, highly cross-linked, spherical PS-DVB,
Particle Size: 50 μm,
Pore Size: 80 Å,
Specific Surface Area: 800 m2/g 		Porous, highly cross-linked, spherical PS-DVB,
Particle Size: 50 μm,
Pore Size: 80 Å
Specific Surface Area: 800 m2/g 		Porous, highly cross-linked, spherical PS-DVB,
Particle Size: 50 μm,
Pore Size: 80 Å,
Specific Surface Area: 800 m2/g 		Porous, highly cross-linked, spherical PS-DVB,
Particle Size: 50 μm,
Pore Size: 80 Å,
Specific Surface Area: 800 m2/g 		Porous, highly cross-linked, spherical PS-DVB,
Particle Size: 50 μm,
Pore Size: 80 Å,
Specific Surface Area: 800 m2/g
Functional group
Retention mechanism Non-polar and polar interactions Non-polar interaction and cation exchange Non-polar interaction and anion exchange Non-polar interaction and weak cation exchange Non-polar interaction and weak anion exchange
Application Pharmaceutical residues in animal tissue, such as tetracyclines, chloromycetin, sulfonamides, abamectin, macrolide antibiotics, nitrofurans, and pesticides in vegetables. Basic compounds, such as sulfonamides and clenbuterol Biological samples, pharmaceuticals, and metabolites in plasma, serum, or urine Compounds with groups as carboxyl and phenolic hydroxyl Strong basic compounds, quaternary ammonium salts For purification of strong acidic compounds

More material with respect to application will available on request.

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